Dr Roger Carpenter
Senior Lecturer in Human Physiology
Physiology and Drug Science, Health, Sport and Bioscience
Dr Carpenter is an applied human physiologist who teaches at all levels of Undergraduate and Postgraduate Bioscience related degrees at UEL. He is an active researcher and has recently worked with colleagues from The university of Kent looking at the effects of muscle fatigue on metabolic responses to exercise (http://dx.doi.org/10.3389/fphys.2016.00463) and is currently working on a feasibility study investigating the effects of physical training on patients with Crohn's disease (funded by Crohn's and Colitis UK, https://crohnsandcolitis.org.uk/research/take-part-in-research/exercise-and-crohns-disease). This work involves collaborations with the University of Hertfordshire, The University of Northumbria, University of York, University of Winchester and associated NHS trusts (e.g., GSST and Barts). His past and present administrative duties include being School of Health Sport and Bioscience quality lead and a module leader in the Physiology and drug science subject area. Dr Carpenter is a keen cyclist and triathlete and is currently chair of the UEL Triathlon club that includes staff, students and members of our local community.
Poster presentation; The Metabolic Profiling of Exercise Intervention: Exercise Metabolomics .
Biomedical basis of elite performance conference, Queen Elizabeth II conference centre London UK March 2012.
Exercise stress induces change in muscle biochemistry to meet the metabolic demands of the working muscles (1). Such change can be observed directly from the presence of biomarkers elucidated from change in
protein and metabolite profiles, light weight molecular products of metabolism, in muscle cells(2) and biofluids(3). The majority of previous research in the biochemical monitoring of sport and exercise has relied on observing change in targeted (pre-selected) metabolites, which provides a modest amount of data on metabolic change.
Advances in bioanalytical technology presents metabolomic techniques as effective tools to provide multidimensional data of all metabolite profiles in minute biological
samples(4), which has unprecedented potential to monitor exercise-induced biochemical change. Metabolomic techniques include gass/liquid chromatography-mass spectrometry (GC/LC-MS) and nuclear magnetic resonance spectroscopy (NMR). In order to establish current status of this research area, a literature search was carried out and presented in this poster.
Objective and Expected Outcomes/Benefits for this PhD Research
To develop metabolomic protocols to profile change in blood, urinary and salivary metabolites induced by isolated muscle contractions. The aim is to establish reliable protocols to standardise the identification of biomarkers allied to sport, exercise and rehabilitation.
The expected outcome/benefit of this PhD programme of research is that it will contribute to the future design of biochemical monitoring in sport, exercise and rehabilitation.
Whyte, J.J. and Laughlin, M.H. (2010) The effects of acute and chronic exercise on the vasculature. Acta
Green, H.J., Bombardier, E., Burnett, M.E., Smith, I.C., Tupling, S.M., and Ranney, D.A. (2009) Time-dependent effects of short term training on muscle metabolism during early phase of exercise. Am J Physiol Regul Interg Comp Physiol, 297:1318-1391.
Neary, J.P., Malbon, L. and McKenzie, D.C. (2002) Relationship Between Serum, Saliva and Urinary Cortisol and its Implication During Recovery from Training. Journal of Science and Medicine in Sport, 5(2):108-114.
Corcoran, O. and Spraul, M. (2003) LC-NMR-MS in drug discovery. Drug Discovery Today, 8:624-631.
Papacosta, E. and Nassis, G.P. (2011) Saliva as a tool for monitoring steroid, peptide and immune markers in sport and exercise science. Journal of Science and Medicine in Sport, 14:424-434.
Publications Kass. L and R. Carpenter (2009). The effect of sampling time on blood lactate concentration in trained rowers. International Journal of Sports Physiology and Performance Vol. 4(1), March.
Cousins, S., Johnstone, J., Hastings, K., Carpenter, R., & P. A. Ford. (2008). Performance and anthropometric characteristics of junior track and field athletes. BASES Annual Conference.
Carpenter, R. (1995) Accumulated oxygen deficit and short distance running performance in young middle-distance runners. Poster communication BASES Annual Conference, Birmingham, UK
Carpenter, R. (1997). Effects of workload intensity and duration on the VO2-workload regression. Oral communication; Federal Institute of Medicine and Science in Sport: Annual Conference, Monaco
Carpenter, R. (1996). The slow rise in VO2 during constant running exercise above and below the Ventilatory threshold: Poster communication BASES Annual Conference, Lilleshall, UK
MSc Thesis (1992): Accumulated oxygen deficit and short distance running performance in young middle-distance runners.
PhD Thesis (2001): Methodological effects on the VO2-workload regression and maximal accumulated oxygen deficit (MAOD)