Dr Mukhlesur Rahman
Associate Professor
Research Group Lead of Medicines Research Group
Department of Bioscience , School Of Health, Sport And Bioscience
Dr Mukhlesur Rahman is an Associate Professor in Pharmaceutical and Natural Product Chemistry and Subject Area Lead of Drug and Chemical Sciences. He has also led the Medicines Research Group since 2020. At UEL, he designed and developed both BSc (Hons) Pharmaceutical Science and MSc Pharmaceutical Science and served as Programme Leader for both courses between 2012-2019.
Qualifications
- BPharm (Hons) with First Class
- MPharm with First Class
- PhD
Areas Of Interest
- Bioassay guided isolation and identification of anti-infective lead compounds from medicinal plants
- Bioactive secondary metabolites from the cultural broth of microbes
- Synthesis of bioactive natural products and their analogues
- Application of 1D and 2D NMR spectroscopy in drug discovery
- Ethnopharmacological surveys to exploit indigenous knowledge in drug discovery
- Applications of HPLC, UPLC, LCMS and GSMS in the quality control of herbal medicines
OVERVIEW
Mukhlesur Rahman completed his Bachelor of Pharmacy (Hons) and Master of Pharmacy with first class from the University of Dhaka. He completed PhD in Natural Product Chemistry from the University of Strathclyde with Commonwealth Scholarship and worked as a postdoctoral research fellow (over 3 years) at the School of Pharmacy, University of London (currently known as UCL School of Pharmacy).
Dr Rahman has over 17 years of teaching experience in Higher Education Institutions (University of East London, Liverpool John Moores University and Rajshahi University). He also has three years of industrial experiences in pharmaceutical (Organon) and biotechnology (Novacta Biosystem). With his academic and industrial experiences, he designed and developed two brand new courses (BSc (Hons) Pharmaceutical Science and MSc Pharmaceutical) at UEL. Between 2012-2019, he served as Programme Leader of both BSc (Hons) and MSc Pharmaceutical Science courses. Over the years he was involved in curricula developments, validation and revalidation processes for these courses. He has led several new modules over the years.
Dr Rahman is leading the Medicines Research Group at UEL and also leading the Health Sport and Bioscience seminar series. With significant research responsibility, he has established strong research collaboration with top UK universities and organizations including UCL, Strathclyde, Birkbeck, Kew Botanical Garden and Liverpool John Moores University. Outside the UK, he collaborates with several universities in India, Bangladesh, China, Nigeria and Ghana. Dr Rahman is currently serving as associate editor of Journal of Herbal Medicine, Frontiers in Pharmacology and topic editor in Frontiers in Pharmacology on the research topic Natural Products as Potential Therapeutics to Tackle Life-Threatening Infections: From Field to Market.
Dr Rahman has published over 90 research outputs (citations 3,066; h-index 32) and presented his research findings at several international research conferences as invited/ plenary speaker. His outputs have been included in the UEL REF2021 submission under UoA3. Dr Rahman has received the Society for Ethnopharmacology (affiliated to International Society of Ethnopharmacology) annual award (SFE T. Sen Oration award 2021) in recognition of his significant research contribution in the areas of Natural Products Chemistry and Ethnopharmacology.
CURRENT RESEARCH
Dr Rahman's research outputs have been included in the recent REF submission under UoA3.
Funded by The British Council and The Royal Society of Chemistry through the Newton grant, Dr Rahman led in recruiting 24 early career researchers (ECRs) from UK and India and organizing 4 days workshops on "Scopes and challenges for the development of novel antimicrobial agents from Ayurvedic medicinal plants to combat the problem of antimicrobial resistance" at Jadavpur University, India. The event facilitated networking among ECRs and scientists, RSC and British Council officials, physicians and herbal manufacturers.
With QR GCRF fund, Dr Rahman worked with five ODA partners in Bangladesh, India and China and generated data through AMR awareness and ethnopharmacological surveys which were shared among the ODA partners through an AMR workshop at Dhaka University (March 2019) facilitating social engagement with health professionals and traditional practitioners.
Funded by the Indian Council of Agricultural Research (ICAR), Dr Rahman's recent postdoctoral fellows are working on the therapeutic evaluation of some North-East Indian medicinal plants for the identification of compounds responsible for antibacterial properties against methicillin resistance Staphylococcus aureus.
Dr Rahman's current PhD students are working on medicinal plants - one project on Ghanaian medicinal plants for the identification of antimicrobial compounds against clinical isolates of multidrug resistance (MDR) and methicillin resistance Staphylococcus aureus (MRSA) and another project on medicinal plants to characterize anticancer compounds against skin and breast cancer cell lines.
Dr Rahman's main research area is natural product chemistry with particular focus on anti-infective drug discovery from natural resources. His research interests include bioassay directed isolation, purification and identification of antibacterial metabolites from medicinal plants and microbes.
Research and impact
Dr Rahman has been working on numerous medicinal plants from different parts of the world for the isolation and characterization of bio-active metabolites belonging to a variety of chemical classes with potential activities against a series of clinical isolates of multi-drug resistance (MDR) and methicillin resistance Staphylococcus aureus (MRSA). Some of the compounds isolated and identified by Dr Rahman and his collaborators revealed their potentials as efflux pump inhibitors (EPIs). In order to confirm the structures of the compounds of natural products, Dr Rahman exploits high field NMR (both 1D and 2D) spectroscopy and mass spectrometry. He is also involved in the total synthesis of highly active natural products and their analogues to fit them for SAR study.
Dr Rahman’s research interest also includes ethnopharmacological survey to exploit the indigenous knowledge of traditional practitioners and/or traditional healers in drug discovery by identifying the medicinal plants that are being recommended for the treatment of infectious diseases. His group conducted such an ethnopharmacological survey in Bangladesh. Another similar survey will be carried out in Ghana to identify the medicinal plants that are being recommended by local healers for the treatment of various infections. Dr Rahman is also interested in propolis for anti-infective drug discovery.
Dr Rahman has published over 90 research outputs (citations 3,066; h-index 32; source- Google Scholar) in peer reviewed journals including Q1 and Q2 journals. He presented his research findings at several international research conferences in UK, USA, Switzerland, Austria, Greece, Bangladesh and India as invited/ plenary speaker. His research has been included in the AD Scientific Index 2022 and ranked 9th in University of East London. He is currently serving as associate editor of Journal of Herbal Medicine, Frontiers in Pharmacology and topic editor for an issue in Frontiers in Pharmacology. Dr Rahman successfully supervised two PhD projects (one as DoS and another PhD as host supervisor during PhD placement) and two MRes projects to completion on time. He also supervised two postdoctoral fellows and hosted five professional fellows at UEL.
Dr Rahman currently has two PhD students as DoS, one PhD and two MRes students as 2nd supervisor. He is also supervising one postdoctoral fellow and is expecting two more postdoctoral fellows to start shortly.
PhD Completion:
- Dr Holly Siddique (2016-2019) - Currently working as a postdoc at Royal Botanical Garden Kew
- Jayded Chanda (2016-2020) - Currently working as a research scientist at Royal Botanical Garden Kew
MRes Completion:
- Miss Oneza Saleem (2018-2019) - Currently doing PhD
- Mr Rayhan Parvez Currently working as microbiologist in the NHS
Current PhD and MRes students:
- Miss Oneza Saleem - (PhD project as DoS) Started in Feb 2021
- Mr Rexford OSAE-TWUM - (PhD project as DoS) Started in Oct 2021
- Miss Misaki Seto - (PhD project as 2nd supervisor) Started in 2019
- Mr Hamid Kashkooli (MRes project as 2nd supervisor) Viva will take place soon
- Mr Farrukh Makhamadjonov (MRes project as 2nd supervisor) Started in Oct 2021
Postdoctoral and mid-career professional fellows
- Dr Ekramul Haque (2013) - Funded by Commonwealth Scholarship Commission. Worked at University of Rajshahi (Bangladesh)
- Dr Fakir Shahidullah Tareq (2016) - Funded by Georg Forster Research Fellowship. Currently working as Research Associate at US Dept. of Agriculture (USDA) affiliated with University of Maryland
- Dr Rashedul Haque (2017) - Funded by Commonwealth Scholarship Commission. Currently working as a Professor at University of Dhaka (Bangladesh)
- Dr Sharifur Rahman (2017) - Funded by Commonwealth Scholarship Commission. Currently working as a Professor at University of Dhaka (Bangladesh)
- Dr Abdul Alim Al-Bari (2017) - Funded by Commonwealth Scholarship Commission. Currently working as a Professor at University of Rajshahi (Bangladesh)
- Dr Afzal Basha Shaik (2017) - Funded by Commonwealth Scholarship Commission. Currently working as a Professor at Vignan Pharmacy College (India) Dr Kandarpa Kr. Saikia (2017)- Funded by Commonwealth Scholarship Commission. Currently working as an Associate Professor at Gauhati University (India)
- Dr Purabi Kaushik (2022) - Current postdoc (funded by Indian Council of Agricultural Research; ICAR)
- Dr Sutopa Das (2022) - This postdoctoral fellow (funded by Indian Council of Agricultural Research; ICAR) is expected to join shortly
- Dr Nikhil Ch. Nath (2022) - This postdoctoral fellow (funded by Indian Council of Agricultural Research; ICAR) is expected to join shortly.
With an international research profile in antimicrobial drug discovery from natural products and collaborations in the UK and abroad, Dr Rahman is working towards the development of an impact case on antimicrobial resistance.
PUBLICATIONS
Publications
- ResearchGate articles
- Scopus No.: 56249512100
- Google Scholar URL
- Web of Science Researcher ID
- Total citations- 3,066 in Google Scholar; 2,029 in Scopus
- h-index- 32 in Google Scholar; 26 in Scopus
- h10-index- 53 (Source- Google Scholar)
- Total number of Peer review Journal articles: 92
- Number of book chapters - 4
- Number of conference papers - 23 (Award winning lecture-1; Invited speaker- 5; Plenary-4; Oral/ Poster presentations- 13)
- Chairing/ co-chairing scientific sessions in conference/ symposium/ workshops - 8
Journal articles
2022
- Shaik, A. B., Lagu, S. B., Yejella, R. P., Nissankararao, S., Bhandare, R. R., Golla, V. S., Lokesh, B. V. S., and Rahman, M. M. (2022) Antitubercular activity assessment of fluorinated chalcones, 2‐aminopyridine‐3‐carbonitrile and 2‐amino-4H-pyran‐3‐carbonitrile derivatives: In vitro, molecular docking and in-silico drug likeliness studies, PLOS One (in press)
- Saha, P., Rahman, F. I., Hussain, F., Rahman, S. M. A. and Rahman, M. M. (2021) Antimicrobial diterpenes: a systematic review on the recent development from natural sources, Frontiers in Pharmacology
2021
- Siddique, H., Pendry, B., Rashid, M. A. and Rahman, M. M., (2021) Medicinal plants used to treat infectious diseases in the central part and a northern district of Bangladesh - An ethnopharmacological perception, Journal of Herbal Medicine, 29, 100484.
- Al-Majmaie, S., Nahar, L., Rahman, M. M., Nath, S., Saha, P., Talukdar, A. D., Sharples, G. P. and Sarker, S. D. (2021) Anti-MRSA constituents from Ruta chalepensis (Rutaceae) grown in Iraq, and in Silico studies on two of most active compounds, chalepensin and 6-hydroxy-rutin 3',7-dimethyl ether, Molecules 26, 1114.
- Shaik, A. B., Bhandare, R. R., Nissankararao, S., Lokesh, B. V. S., Shahanaaz, S. and Rahman, M. M. (2021) Synthesis and biological screening of chloropyrazine conjugated benzothiazepine derivatives as potential antimicrobial, antitubercular and cytotoxic agents, Arabian Journal of Chemistry, 14(2), 102915.
2020
- Shaik, A. B., Bhandare, R. R., Nissankararao, S., Edis, Z., Tangirala, N. R., Shahanaaz, S. and Rahman, M. M. (2020) Design, facile synthesis and characterization of dichloro substituted chalcones and dihydropyrazole derivatives for their antifungal, antitubercular and antiproliferative activities, Molecules, 25(14), 3188.
2019
- Siddique, H., Pendry, B., and Rahman, M. M., (2019) Terpenes from Zingiber montanum and their screening against multi-drug resistant and methicillin resistant Staphylococcus aureus, Molecules, 24(3), 385.
2018
- Danquah, C. A., Kakagianni, E., Khondkar, P., Maitra, A., Rahman, M. M., Evangelopoulos, D., McHugh, T. D., Stapleton, P., Bhakta, S. and Gibbons, S. (2018) Analogues of disulfides from Allium stipitatum demonstrate potent anti-tubercular activities through drug efflux pump and biofilm inhibition, Scientific Reports 8, 1150.
- Rahman, M. M., Shiu, W. K. P., Malkinson, J. P., Gibbons, S. (2018) Total synthesis of acylphloroglucinols and their antibacterial activities against clinical isolates of multi-drug resistant (MDR) and methicillin-resistant strains of Staphylococcus aureus, European Journal of Medicinal Chemistry 155, 255-262.
- Tareq, F. S., Hasan, C. M., Rahman, M. M., Hanafi, M. M. M., Spiteller, P. (2018) Anti-staphylococcal Calopins from fruiting bodies of Caloboletus radicans, Journal of Natural Products, 81 (2), 400–404.
- Nurunnabi, T., Nahar, L., Al-Makmaie, S., Rahman, S. M. M., Sohrab, M. H., Billah, M.M., Ismail, F.M.D., Rahman, M. M., Sharples, G, P. and Sarker, S.D. (2018) Anti-MRSA activity of oxysporone and xylitol from the endophytic fungus Pestalotia sp. growing on the Sundarbans mangrove plant Heritiera fomes, Phytotherapy Research, 32 (2), 348-352.
2016
- Mundy, L., Pendry, B. and Rahman, M. M. (2016) Antimicrobial resistance and synergy in herbal medicine, Journal of Herbal Medicine, 6(2), 53–58. https://doi.org/10.1016/j.hermed.2016.03.001
2015
- Rahman, M. M. and Gibbons, S. (2015) Antibacterial constituents of Neohyptis paniculata, Fitoterapia 105, 269-272. https://doi.org/10.1016/j.fitote.2015.07.012
2014
- Xia, H., Sun, L., Lou, H. and Rahman, M. M. (2014) Conversion of salvianolic acid B into salvianolic acid A in tissues of Radix Salviae Miltiorrhizae using high temperature, high pressure and high humidity, Phytomedicine 21(6), 906-11. https://doi.org/10.1016/j.phymed.2014.01.005
2013
- Shiu, W. K. P., Malkinson, J. P., Rahman, M. M., Curry, J., Stapleton, P., Gunaratnam, M., Neidle, S., Mushtaq, S., Warner, M., Livermore, D. M., Evangelopoulos, D., Basavannacharya, C., Bhakta, S., Schindler, B. D., Seo, S. M., Coleman, D., Kaatz, G. W., Gibbons, S. (2013) A new plant-derived antibacterial is an inhibitor of efflux pumps in Staphylococcus aureus, International Journal of Antimicrobial Agents 42 (6), 513-518. https://doi.org/10.1016/j.ijantimicag.2013.08.007
2012
- Shiu, W. K. P., Rahman, M. M., Curry, J., Stapleton, P., Zloh, M., Malkinson, J. P., Gibbons, S. (2012) Antibacterial acylphloroglucinols from Hypericum olympicum, Journal of Natural Products 75 (3), 336–343. https://doi.org/10.1021/np2003319
- Ioannou, E., Quesada, A., Rahman, M. M., Gibbons, S., Vagias, C. and Roussis, V. (2012) Structure and antibacterial activities of minor dolabellanes from the brown alga Dilophus spiralis, European Journal of Organic Chemistry 27, 5177-5186. https://doi.org/10.1002/ejoc.201200533
2011
- Garvey, M. I., Rahman, M. M., Gibbons, S. and Piddock, L. J. V. (2011) Medicinal plant extracts with efflux inhibitory activity against Gram negative bacteria, International Journal of Antimicrobial Agents 37 (2), 145-151.
- Guzman, J. D., Wube, A., Evangelopoulos, D., Gupta, A., Hüfner, A., Basavannacharya, C., Rahman, M. M., Thomaschitz, C., Bauer, R., McHugh, T. D., Nobeli, I., Prieto, J. M., Gibbons, S. Bucar, F. and Sanjib Bhakta, S. (2011) Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics, Journal of Antimicrobial Chemotherapy 66 (8), 1766–1772.
- Ioannou, E., Quesada, A., Rahman, M. M., Gibbons, S., Vagias, C. and Roussis, V. (2011) Dolabellnes with antibacterial activity from the brown alga Dilophus spiralis, Journal of Natural Products 74 (2), 213-222.
- Delazar, A., Delnavazi, M. R., Nahar, L., Moghadam, S. B., Mojarab, M., Gupta, A., Williams, A. S., Rahman, M. M. and Sarker, S. D. (2011) Lavandulifolioside B: a new phenylethanoid glycoside from the aerial parts of Stachys lavandulifolia Vahl. Natural Product Research 25 (1), 8–16.
- Begum, R., Kaisar, M. A., Rahman, M. S., Chowdhury, A. M. S., Rahman, M. M., Hasan, C. M., and Rashid, M. A. (2011) Clausenolide-1-methyl ether from Clausena heptaphylla W & A The Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants (BLACPMA) 10 (2): 136 -138.
Book Chapters
- Kar, A., Banerjee, R., Devi, I., Pulok K Mukherjee, P. K. and Rahman, M. M. (2022) Medicinal plants in antimicrobial resistance- perspectives towards drug development In: Mukherjee, P. K. (ed), Evidence-Based Validation of Herbal Medicine: Amsterdam, Oxford and, Waltham: Elsevier, (in press)
- Rahman, M. M. and Sarker, S. D. (2020) Chapter Three - Antimicrobial natural products. In: Sarker, S. D. and Nahar, L. (eds), Annual reports in Medicinal Chemistry: Amsterdam, Oxford and, Waltham: Elsevier, Vol. 55, Chapter 3, pp 77-113. ISBN: 978-0-12-821019-2.
- Rahman, M. M. (2018) Application of computational methods in isolation of plant secondary metabolites. In: Sarker, S. D. and Nahar, L. (eds), Computational Phytochemistry: Amsterdam, Oxford and, Waltham: Elsevier, Chapter 4, pp 107-139. ISBN: 9780128123645.
- Rahman, M. M. (2014) Antimicrobial secondary metabolites - extraction, isolation, identification and bioassay. In: Mukherjee, P. K. (ed), Evidence-Based Validation of Herbal Medicine: Amsterdam, Oxford and, Waltham: Elsevier, pp 495-513. ISBN: 9780128008744.
Conference abstracts and presentations
Plenary and Invited lectures
- Rahman, M. M. (2021) 'Natural products to tackle the challenges of antimicrobial resistance (AMR)', Delivered award winner lecture (SFE-Prof T. Sen Memorial Award 2021) at the 8th International Congress of the Society for Ethnopharmacology, India (SFEC 2021) held at Pune, Maharashtra, India during August 27-29, 2021(delivered online).
- Rahman, M. M. (2020) 'Natural products for global issue of antimicrobial resistance', Delivered a lecture as an invited guest in the XXXV AICTE Sponsored Quality Improvement Program (QIP) on "Frontiers in Pharmaceutical in Education and Research: Emerging trends in Phytopharmaceuticals" at the Delhi Pharmaceutical Sciences and Research University on October 9-16, 2020 (online).
- Rahman, M. M. (2018) 'Zingiber montanum: from an ethnopharmacological survey to the bioassay directed identification of secondary metabolites', Delivered a lecture in the Phytochemical Society of Europe’s conference on 'Advances in Phytochemical Analysis-Trends in Natural Products Research' at Liverpool John Moores University on July 2-5, 2018.
- Rahman, M. M. (2018) ‘Anti-infective medicinal plants of Bangladesh- an ethnopharmacological survey, chemistry and bioassay’. Delivered a lecture in the 18th International Congress of the International Society for Ethnopharmacology at the University of Dhaka, Bangladesh on January 13-15, 2018.
- Rahman, M. M. (2016) ‘Antibiotics resistance and plant derived secondary metabolites’. Delivered a lecture in the 7th World Ayurveda Congress & AROGYA Expo (7th WAC) on ‘Ethnopharmacology, Ethnomedicine and Traditional Health Practices’ at Science City, Kolkata, India on December 3-4, 2016.
- Rahman, M. M. (2016) ‘Antimicrobial resistance, traditional medicines and plant derived antibacterial secondary metabolites’. Delivered a plenary lecture in the joint international conference on ‘Applications of Natural Products and Opportunities Ahead’ at BS Abdur Rahman University (India) in August 2-3, 2016.
- Rahman, M. M. (2015) ‘Plant derived new antibacterial secondary metabolites- isolation, identification and total synthesis’. Delivered a lecture in the ‘CHEMRAWN XX -20th IUPAC conference on Chemical Research Applied to World Needs’ at Bangladesh University of Health Sciences, Dhaka on November 06-09, 2015.
- Rahman, M. M. (2015) ‘Plant derived secondary metabolites against multi-drug resistant (MDR) and methicillin resistant Staphylococcus aureus (MRSA)’ Delivered a plenary lecture as an invited guest in the 19th Annual Convention and 2nd International Conference of the Society of Pharmacognosy at Andhra University, India on March 20 - 22, 2015.
- Rahman, M. M. (2014) ‘Antibacterial secondary metabolites from indigenous medicinal plants’. Delivered a plenary lecture as an invited guest in the 1st International Congress of the Society for Ethnopharmacology (ICSE 2014) on “Globalizing Traditional Medicine: present and Future Prospects” at Sri Ramachandra University, India on March 07-09, 2014.
- Rahman, M. M. (2013) ‘Antibacterial lead compounds from medicinal plants’. Delivered a plenary lecture in an international conference on “Updates on Natural Products in Medicine and Healthcare systems” organized by Biotechnology and Genetic Engineering Discipline, Khulna University, Bangladesh on July 06-07, 2013.
Podium/ Oral presentations and poster presentations
- Siddique, H., Pendry, B., and Rahman, M. M., (2018) Antibacterial mono- and sesqui-terpenes from Zingiber montanum; A poster presented in the Phytochemical Society of Europe conference on ‘Advances in Phytochemical Analysis -Trends in Natural Products Research)’ at Liverpool John Moores University on July 2-5, 2018.
- Siddique, H., Pendry, B., Tocher, J., and Rahman, M. M., (2017) Anti-infective medicinal plants- an ethnopharmacological survey in Bangladesh. Both podium and poster presented at the APSGB 8th International PharmSci Conference 2017 at the University of Hertfordshire on September 5-7, 2017.
- Rahman, M. M., Shiu, W.K.P., Gibbons, S. and Malkinson, J. P. (2015) Synthesis of acylphloroglucinols and their antibacterial activities against clinical isolates of MRSA strains. Poster presented at the ASP2015 meeting in Copper Mountain, Colorado, USA on July 25 - 29, 2015; Abstract published in Planta Medica 81(11): PZ1.
- Garvey, M. I., Rahman, M. M., and Gibbons, S. and Piddock, L. J. V. (2010) Plant extracts that synergize with antibiotics against Gram-negative bacteria. Poster presented at the Annual Meeting of the Society for General Microbiology at Harrogate International Centre, UK on March 30- April 2, 2009, p-59.
- Pereda-Miranda, R., Escobedo-Martínez, C., Cruz-Morales, S., Fragoso-Serrano, M., Rahman, M. M. and Gibbons, S. (2009) Characterization of a xylose containing resin glycoside isolated from Ipomoea pes-caprae. Poster presented at the 50th Anniversary Meeting of the American Society of Pharmacognosy in Honolulu, USA on June 27 - July 1, 2009, p-047.
- Rahman, M. M. and Gibbons, S. (2008) Constituents of Neohyptis paniculata and their anti-staphylococcal activity. Poster presented at the 7th Joint Meeting of AFERP, ASP, GA, PSE & SIF in Athens, Greece on August 03-08, 2008; Abstract published in Planta Medica 74 (9): 1048.
- Ioannou E., Vagias C., Rahman, M. M., Gibbons, S. And Roussis, V. (2008) New dolabellanes from the brown alga Dilophus spiralis. Poster presented at the 7th Joint Meeting of AFERP, ASP, GA, PSE & SIF held in Athens, Greece on August 03-08, 2008; Abstract published in Planta Medica 74 (9): 1053.
- Rahman, M. M. and Gibbons, S. (2007) The anti-staphylococcal activity of terpenes from Commiphora molmol. Poster presented at the 55th International Congress and Annual Meeting of the Society for Medical Plant Research at Graz, Austria on September 02-06, 2007; Abstract published in Planta Medica 73 (9): 872.
- Rahman, M. M. and Gray, A. I. (2003) Antimicrobial compounds from Bangladeshi legumes. An oral presentation at the 2nd Phytotherapy Research Conference organized by Bioforce (UK) Ltd at the Royal Concert Hall, Glasgow, UK on March 27-28, 2003.
- Rahman, M. M. and Gray, A. I. (2002) Antimicrobial carbazoles from Murraya koenigii. Poster presented at Phytotherapy Research Conference organized by Bioforce (UK) Ltd at the Royal Concert Hall, Glasgow, UK on April 19, 2002. 21.
- Rahman, M. M. and Gray, A. I. (2001) Novel isoflavanones from Uraria picta. Poster presented at the International Symposium of the Phytochemical Society of Europe at the Institute of Pharmacognosy and Phytochemistry, University of Lausanne, Switzerland on September 12-14, 2001, p 078. 22.
- Khatune, N. A., Haque, M. E., Mosaddik, M. A., Rahman, M. M. and Gray, A. I. (2000) Isolation of two new compounds, a coumesterol derivative and a benzaldehyde derivative from Psoralea corylifolia Linn. Poster presented at the 10th Asian Symposium on ‘Medicinal Plants and other Natural Products on Research and Development of Natural Products for Human Survival in the 21st Century’ in the University of Dhaka, Bangladesh on November 18-23, 2000, p 282.
- Rahman, M. M., Gray, A. I., Drummond, A. J. and Khondkar, P. (2000) Antimicrobial constituents from Feronia limonia. Poster presented at the 35th annual PSNA conference and 16th annual MAPMBS meeting symposium on Regulation of Phytochemicals by Molecular Techniques at USDA Beltsville Agricultural Research Center, Beltsville, MD 20705, USA on August 6-10, 2000, pp 17-18.
TEACHING
EXTERNAL ROLES
- Research Degree (PhD/ MRes) External examiner - UCL School of Pharmacy (4 PhD), University of Strathclyde (4 PhD and 1 MRes), University of Bradford (3 PhD), King’s College London (2 PhD), University of Huddersfield (1 PhD), University of Queensland (1 PhD)
- External examiner - Pharmacy undergraduate (BPharm; 2005-2006) and Pharmacy postgraduate (MPharm; 2006) at University of Dhaka
- Deputy Chair, the APSGB research focus group on 'Drugs from Natural Sources' (2016-2018)
- Associate Editor, Journal of Herbal Medicine
- Associate Editor, Frontiers in Pharmacology - Experimental Pharmacology and Drug Discovery
- Guest Associate Editor, Frontiers in Pharmacology - Ethnopharmacology
- Topic Editor, Frontiers in Pharmacology - Natural Products as Potential Therapeutics to Tackle Life - Threatening Infections: From Field to Market
- Editorial board member (2016-2019), Journal of Herbal Medicine
- Journal reviewer - Scientific Report, Frontiers in Pharmacology, Journal of Ethnopharmacology, Pharmaceutical Biology, Phytochemical Analysis, Phytochemistry letters, Natural Product Communications
FUNDING
- Indian Council of Agricultural Research (ICAR) (2021)- $ 55,051
- UEL - Industry matched KE fund (2021) - £82,043 (UEL £34,500 and Industrial partner £47,543) as PI for an industrial PhD studentship.
- UEL KE mechanisms fund (2021) - £3,250 as PI for Pump Prime CPDs/ Short courses.
- Commonwealth Scholarship Commission (2020) - £36,300 as PI but withdrawn because of impact of COVID19.
- UEL QR GCRF (2018/19)- £12,990 as PI. · AHC College Mini-sabbatical Grant (2018)- £1,000.
- Newton Fund Researcher Links Workshop Grant (2017) - £31,900 as PI.
- Commonwealth Scholarship Commission (2016) - £58,825 as PI.
- Newton-Bhabha PhD Placements grant (2016) - £11,200 as host supervisor.
- HSB PhD Studentship (2015)- £78,171 as lead applicant
- UEL HSB Research and Knowledge Exchange Grants (2014) - £2,810
- Commonwealth Scholarship Commission (2013)- £9,700 as host supervisor
- UEL Undergraduate Summer Internship (2013) – £2,000 as PI.
- UEL Research Development Grant (2012)- £5,000 as Co-I.
MODULES TAUGHT
- BS4100 - Professional Practice in Science
- BS4101 - Essential Chemistry (Module Leader)
- BS4103 - Fundamentals of Analytical Chemistry
- BS5106 - Pharmaceutics and Drug Delivery
- BS5107 - Advanced Topics in Analytical Chemistry
- BS5110 - Research and Career Development
- BS6108 - Natural Products Discovery
- BS6109 - Medicinal Chemistry
- BS6112 - Application of Analytical Techniques in Pharmaceutical Quality Control (Module Leader)
- BS6113 - Research Project and Career Enhancement Portfolio
- BS7200 - Experimental Techniques and Laboratory Practice
- BS7201 - Evidence-Based Practice and Career Development
- BS7204 - Drug Discovery, Design and Development
- BS7209 - Advanced Pharmaceutical Analysis and Quality Control (Module Leader)
Publications
The last four years of publications can be viewed below.
Full publications list
Visit the research repository to view a full list of publications
- Antileprotic drugs in: Acharya, P. C. and Kurosu, M. (ed.) Medicinal Chemistry of Chemotherapeutic Agents: A Comprehensive Resource of Anti-Infective and Anti-cancer Drugs. Academic Press, pp.267-282
- Antitubercular drugs in: Acharya, P. C. and Kurosu, M. (ed.) Medicinal Chemistry of Chemotherapeutic Agents: A Comprehensive Resource of Anti-Infective and Anti-cancer Drugs. Academic Press, pp.217-265
- Bioactivity and In Silico Studies of Isoquinoline and Related Alkaloids as Promising Antiviral Agents: An Insight Biomolecules. 13 (1), p. Art. 17. https://doi.org/10.3390/biom13010017
- Editorial: Natural products as potential therapeutics to tackle life-threatening infections: From field to market Frontiers in Pharmacology. 13 (Art. 1099181). https://doi.org/10.3389/fphar.2022.1099181
- Antitubercular activity assessment of fluorinated chalcones, 2-aminopyridine-3-carbonitrile and 2-amino-4H-pyran-3-carbonitrile derivatives: In vitro, molecular docking and in-silico drug likeliness studies PLoS ONE. 17 (Art. e0265068). https://doi.org/10.1371/journal.pone.0265068
- Antimicrobial Diterpenes: Recent Development From Natural Sources Frontiers in Pharmacology. 12 (Art. 820312). https://doi.org/10.3389/fphar.2021.820312
- Medicinal plants used to treat infectious diseases in the central part and a northern district of Bangladesh - an ethnopharmacological perception Journal of Herbal Medicine. 29 (Art. 100484). https://doi.org/10.1016/j.hermed.2021.100484
- Anti-MRSA Constituents from Ruta chalepensis (Rutaceae) Grown in Iraq, and In Silico Studies on Two of Most Active Compounds, Chalepensin and 6-Hydroxy-rutin 3’,7-Dimethyl ether Molecules. 26 (Art. 1114). https://doi.org/10.3390/molecules26041114
- Synthesis, and biological screening of chloropyrazine conjugated benzothiazepine derivatives as potential antimicrobial, antitubercular and cytotoxic agents Arabian Journal of Chemistry. 14 (Art. 102915). https://doi.org/10.1016/j.arabjc.2020.102915
- Design, Facile Synthesis and Characterization of Dichloro Substituted Chalcones and Dihydropyrazole Derivatives for Their Antifungal, Antitubercular and Antiproliferative Activities Molecules. 25 (Art. 3188). https://doi.org/10.3390/molecules25143188
- Antimicrobial Natural Products in: Sarker, S. and Nahar, L. (ed.) Medicinal Natural Products: A Disease-Focused Approach, Volume 55. Academic Press, pp.77-113