I started my scientific pathway at the University of Glasgow where I studied Immunology for my BSc degree. After a brief spell at Yale University, I embarked on a PhD at Edinburgh University studying the mechanisms behind immunological tolerance to milk proteins. I then moved to London where I worked at the National Institute for Medical Research investigating the signalling pathways involved in positive and negative thymic T cell selection.
From there I changed course slightly to work on endothelial cells and the role anti-apoptotic molecules play, with regards to protecting these cells from immune responses, during transplantation. Continuing within the transplantation field, I moved to King's College London working with Profs Robert Lechler and Giovanna Lombardi. There I continued my research into immune regulation investigating the use of tolerogenic dendritic cells, as well as regulatory T cells, as cellular therapies to induce transplant tolerance. In addition, my other research interests was the intercellular transfer of information between cells and its implications in both a viral and transplant setting. This led to the discovery that viral peptide:MHC class 1 MHC molecules are exchanged between professional antigen-presenting cells highlighting a novel mechanism for spreading antigen during viral infections. In addition, I also investigated how regulatory T cells work and published that these cells can release extracellular vesicles that have immune modulatory properties.